Xiang Zhang, Ph.D
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Xiang Zhang, Ph.D
Director
Positions
- Director
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Lester and Sue Smith Breast Center
- William T. Butler, M.D., Endowed Chair for Distinguished Faculty
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ÔÚÏߺÚÁÏÃÅ
- Professor
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Molecular and Cellular Biology
ÔÚÏߺÚÁÏÃÅ
Houston, TX US
- McNair Scholar
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ÔÚÏߺÚÁÏÃÅ
Houston, Texas United States
- Member
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Dan L. Duncan Comprehensive Cancer Center
Education
- Post-Doctoral Fellowship at Memorial Sloan Kettering Cancer Center
- 06/2011 - New York, New York United States
- PhD from Columbia University
- 05/2006 - New York, New York United States
- BS from Fu-Dan University
- 01/2000 - Shanghai, China, People's Rep
Honors & Awards
- Era of Hope Scholar
- Department of Defense Congressionally Directed Medical Research Programs, Breast Cancer Research Program (03/2016 - 03/2021)
- NIH Pathway to Independence Award (K99/R00)
- National Cancer Institute (09/2010 - 09/2014)
- Career Catalyst Research Award
- Susan G. Komen Foundation (09/2014 - 08/2017)
- Excellence in Research
- Department of Molecular and Cellular Biology, BCM (08/2016)
- Michael E. DeBakey Award for Excellence in Research
- ÔÚÏߺÚÁÏÃÅ (05/2018)
- Sue Eccles Young Investigator Award
- Metastasis Research Society (08/2018)
- Laura Zisken Prize
- Stand Up To Cancer (01/2020 - 01/2021)
- Leadership Award
- Theresa's Research Foundation (10/2016)
Websites
Selected Publications
- Xiang H.-F. Zhang*, X Jin*, S Malladi, YH Wen, E Brogi, M Smid, JA Foekens, and J Massagué. "." Cell. 2013;154(5):1060-73. Pubmed PMID:
- H Wang; C Yu; X Gao; T Welte; A Muscarella; L Tian; J Liu; H Zhao; Z Zhao; J Tao; B Lee; TF Westbrook; STC Wong; JM. Rosen; CK Osborne; Xiang H.-F. Zhang "." Cancer Cell. 2015 Feb 9;27(2):193-210.
- T Welte, IS Kim, L Tian, X Gao, H Wang, J Li, XB Holdman, JI Herschkowitz, A Pond, G Xia, S Kurley, T Nguyen, L Liao, LE Dobrolecki, Q Mo, DP Edwards, S Huang, L Xin, J Xu, Y Li, MT Lewis, T Wang, TF Westbrook, JM Rosen*, and Xiang H.-F. Zhang* "." Nature Cell Biology. 2016 Jun;18:632-644.
- L Tian, A Goldstein, H Wang, IS Kim, HC Lo, T Welte, K Sheng, L Dobrolecki, X Zhang, N Putluri, T Phung, SA Mani, F Stossi, A Sreekumar, MA Mancini, C Zong, WK Decker, MT Lewis, and Xiang H.-F. Zhang "." Nature. 2017 Apr 3;544(7649):250-254.
- H Wang, L Tian, A Goldstein, HC Lo, J Liu, K Sheng, G Zbigniew, F Stossi, C Zong, Z Li, MA Mancini and Xiang H.-F. Zhang "." Nature Communications. 2017;8(15045):DOI: 10.1038/ncomms15045.
- H Wang, L Tian, J Liu, A Goldstein, I Bado, W Zhang, BR Arenkiel, Z Li, M Yang, S Du, H Zhao, DR Rowley, STC Wong, Z Gugala, and Xiang H.-F. Zhang "." Cancer Cell.;34(5):823-839.
- Kim IS, Gao Y, Welte T, Wang H, Liu J, Janghorban M, Sheng K, Niu Y, Goldstein A, Zhao N, Bado I, Lo H-C, ..., Li Y, Mo Q, Westbrook TF, Zong C, Rao A, Sreekumar A, Rosen JM, Zhang XHF "." Nature Cell Biology. 2019 Sep;21(9):1113-1126.
- Lo HC, Xu Z, Kim IS, Pingel B, Aguirre S, Kodali S, Liu J, Zhang W, Muscarella AM, Hein SM, Krupnick AS, Neilsen JR, Paust S, Rosen JM, Wang H, and Xiang H.-F. Zhang "." Nature Cancer. 2020;1:709–722.
- Muscarella MM, Dai W, Mitchell PG, Zhang W, Wang H, Jia L, Stossi F, Mancini MA, Chiu W, and Xiang H.-F. Zhang "." NPG Breast Cancer. 2020 Sep 7;
- Zhang W*, Bado IL*, Hu J, Wan YW, Wu L, Wang H, Gao Y, Jeong HH, Xu Z, Hao X, Lege BM, AI-Ouran R, Li L, Li J, Yu L, Singh S, Lo H-C, Niu M, Liu J, Jiang W, Li Y, Wong STC, Cheng C, Liu Z, Xiang H.-F. Zhang "." Cell. 2021 Apr 19;Online ahead of print(*: Equal contribution)
- Bado IL*, Zhang W*, Wang H, Hu J, Sarkar P, Liu J, Zbigniew G, Xu Z, Zhang W, Li L, Wan YW, Wu W, Lo H-C, Kim IS, Singh S, Janghorban M, Muscarella A, Goldstein A, Singh P, Jeong HH, Liu C, Huang S, Schiff R, Gaber MW, Liu Z, Ellis MJ, Xiang H.-F. Zhang "." Dev. Cell. 2021 Apr 19;56(8):1100-1117 *: equal contribution.
- Zeru Tian, Ling Wu, Chenfei Yu, Yuda Chen, Zhan Xu , Igor Bado , Axel Loredo , Lushun Wang , Hai Wang , Kuan-Lin Wu , Weijie Zhang , Xiang H.-F. Zhang*, Han Xiao* "." Sci. Adv.. 2021 Jun 23;7(eabf2051):* Co-senior authors.
- Zhang W, Zhan X, Hao X, He T, Li J, Shen Y, Liu K, Gao Y, Liu J, Edwards DG, Muscarella AM, Wu L, Yu L, Xu L, Chen X, Wu YH, Bado IL, Ding Y, Aguirre S, Wang H, Gugala Z, Satcher RL, Wong STC, Xiang H.-F. Zhang "." Cancer Discovery. 2023;13(2):474-495.
- Hao X, Shen Y, Chen N, Zhang W, Valverde E, Wu L, Chan HL, Xu Z, Yu L, Gao Y, Bado I, Michie LN, Rivas CH, Becerra-Dominguez L, Aguirre S, Pingel BC, Wu Y-H, Liu F, Ding Y, Edwards DG, Liu J, ..., Shu-Hsia Chen, Mien-Chie Hung, Bora Lim, Xiang H.-F. Zhang "." Cell Stem Cell. 2023;30(5):648-664.
- X Hao, Y Shen, J Liu, ..., Ueno NT, Lim B, Xiang H.-F. Zhang "." Nature Cell Biology. 2024 Nov;26(11):1971-83.
- Yu L, Liebenberg K, Shen Y, Liu F, Xu Z, Wu L, Hao X, Zhang W, Chan HL, Wei B, Lorenzi P, Gao Y, Bado I, Dominguez LB, Rivas CH, Aguirre S, Pingel B, Wu, Y-H, Ding Y, Liu J, Edwards DG, Eberlin LS, and Xiang H.-F. Zhang "Tumor-derived arachidonic acid reprograms neutrophils to promote immune suppression and therapy resistance in triple-negative breast cancer." Immunity. 2025;Accepted
- Liu F, Ding Y, Xu Z, Hao X, Pan T, Miles G, Wu Y-H, Liu J, Bado IL, Zhang W, Wu L, Gao Y, Yu L, Edwards DG, Chan HL, Aguirre S, Dieffenbach MW, Chen E, Shen Y, Hoffman D, Dominguez LB, Rivas CH, Chen X, Wang H, Gugala Z, Satcher RL, Xiang H.-F. Zhang "Single-cell profiling of bone metastasis ecosystems from multiple cancer types reveals convergent and divergent mechanisms of bone colonization.." Cell Genomics. 2025;Accepted.
Memberships
- American Association of Cancer Research
- Member (01/2012)
- Metastasis Research Society
- Member (03/2016)
- American Association of Immunology
- Member (12/2016)
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